Cannabis Use and Epigenetic Changes: Emerging Scientific Insights

Cannabis Use and Epigenetic Changes: Emerging Scientific Insights

Cannabis, one of the most widely used psychoactive substances globally, has garnered significant attention in recent years due to its legalization in various regions and its potential therapeutic applications. However, alongside its growing acceptance, concerns about its long-term effects on human health, particularly at the molecular level, have prompted rigorous scientific investigation. Recent research has revealed that cannabis use is associated with epigenetic changes—modifications to gene expression that do not involve alterations to the underlying DNA sequence. These findings have profound implications for understanding the biological impact of cannabis use and its potential intergenerational effects. This essay explores the evidence linking cannabis use to epigenetic changes, the mechanisms involved, and the broader implications for public health, drawing on recent scientific literature. Epigenetic Modifications: A Brief Overview Epigenetics refers to heritable changes in gene expression that occur without altering the DNA sequence itself. These changes are mediated by mechanisms such as DNA methylation, histone modification, and non-coding RNA regulation, which collectively influence how genes are activated or silenced (Moore et al., 2013). DNA methylation, in particular, involves the addition of methyl groups to cytosine bases in DNA, often suppressing gene expression. Epigenetic modifications are dynamic, influenced by environmental factors such as diet, stress, and substance use, including cannabis (Feinberg, 2018). Given cannabis’s psychoactive properties and its interaction with the endocannabinoid system, researchers have hypothesized that its use could induce epigenetic changes with lasting effects on cellular function and health. Evidence Linking Cannabis Use to Epigenetic Changes Recent studies have provided compelling evidence that cannabis use is associated with alterations in DNA methylation patterns. A landmark study by Schrott et al. (2021) investigated the epigenetic effects of cannabis use in humans and animal models, focusing on DNA methylation in sperm. The researchers found that cannabis users exhibited significant differences in DNA methylation at multiple genomic loci compared to non-users. These changes were particularly pronounced in genes related to neurodevelopment and immune function, suggesting that cannabis use may influence biological processes critical to brain health and immune response (Schrott et al., 2021). Furthermore, the study identified similar methylation patterns in the sperm of rats exposed to tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis, indicating a potential conservation of epigenetic effects across species. Another study by Osborne et al. (2020) explored the impact of cannabis use on epigenetic aging, a measure of biological age derived from DNA methylation patterns. The researchers found that chronic cannabis users exhibited accelerated epigenetic aging compared to non-users, as measured by the Horvath epigenetic clock (Osborne et al., 2020). This finding suggests that cannabis use may contribute to premature cellular aging, potentially increasing the risk of age-related diseases. While the precise mechanisms underlying these changes remain under investigation, the interaction between THC and cannabinoid receptors in the brain and peripheral tissues is thought to play a central role in modulating epigenetic processes (DiNieri et al., 2011). Mechanisms of Cannabis-Induced Epigenetic Changes The endocannabinoid system, which includes cannabinoid receptors (CB1 and CB2), is a key mediator of cannabis’s physiological effects. THC binds to CB1 receptors in the brain, altering neurotransmitter release and influencing gene expression through downstream signaling pathways (Pertwee, 2008). These pathways, including the mitogen-activated protein kinase (MAPK) and phosphoinositide 3-kinase (PI3K) cascades, can modulate epigenetic machinery, such as DNA methyltransferases and histone deacetylases (D’Addario et al., 2013). For instance, chronic THC exposure has been shown to alter histone acetylation in the hippocampus, a brain region critical for memory and learning, potentially contributing to cognitive impairments observed in long-term cannabis users (Prini et al., 2018). Moreover, cannabis use may induce oxidative stress and inflammation, both of which are known to influence epigenetic modifications (Feinberg, 2018). Oxidative stress can disrupt DNA methylation by altering the availability of methyl donors, such as S-adenosylmethionine (SAM), while inflammation may upregulate enzymes that modify histone proteins (Moore et al., 2013). These molecular changes provide a plausible mechanism by which cannabis use could lead to persistent epigenetic alterations, potentially affecting not only the user but also their offspring through transgenerational epigenetic inheritance (Schrott et al., 2021). Implications for Public Health and Future Research The discovery of cannabis-associated epigenetic changes raises important considerations for public health, particularly in the context of increasing cannabis legalization and use. Epigenetic modifications in sperm, as observed by Schrott et al. (2021), suggest that cannabis use may have intergenerational effects, potentially influencing the health and development of offspring. For example, altered methylation in neurodevelopmental genes could increase the risk of neurodevelopmental disorders in children of cannabis users, a hypothesis that warrants further investigation. Similarly, the accelerated epigenetic aging reported by Osborne et al. (2020) underscores the need to assess the long-term health risks of chronic cannabis use, particularly in relation to cardiovascular and neurodegenerative diseases. Despite these findings, significant gaps in knowledge remain. The reversibility of cannabis-induced epigenetic changes, the dose-response relationship, and the impact of different cannabis constituents (e.g., THC vs. cannabidiol) are areas that require further exploration. Longitudinal studies are needed to determine whether these epigenetic changes persist after cessation of cannabis use and to elucidate their clinical significance. Additionally, research should investigate the role of environmental and lifestyle factors, such as diet and stress, in modulating cannabis-related epigenetic effects. Conclusion Emerging evidence suggests that cannabis use is linked to epigenetic changes, particularly in DNA methylation patterns, with potential implications for neurodevelopment, immune function, and biological aging. These findings highlight the complex interplay between cannabis, the endocannabinoid system, and epigenetic regulation, underscoring the need for caution in the context of widespread cannabis use. While current research provides valuable insights, further studies are essential to fully understand the scope and reversibility of these epigenetic changes and their impact on individual and public health. As cannabis legalization continues to expand, integrating these scientific findings into public health policy and education will be critical to promoting informed decision-making and mitigating potential risks.

### References D’Addario, C., DiNieri, J. A., & Hurd, Y. L. (2013). Epigenetic regulation of gene expression in the brain by drugs of abuse. *Neuropsychopharmacology*, 38(1), 167–183. https://doi.org/10.1038/npp.2012.167 DiNieri, J. A., Wang, X., Szutorisz, H., Spano, S. M., Kaur, J., Casaccia, P., ... & Hurd, Y. L. (2011). Maternal cannabis use alters ventral striatal dopamine D2 gene regulation in the offspring. *Biological Psychiatry*, 70(8), 763–769. https://doi.org/10.1016/j.biopsych.2011.06.007 Feinberg, A. P. (2018). The key role of epigenetics in human disease prevention and mitigation. *New England Journal of Medicine*, 378(14), 1323–1334. https://doi.org/10.1056/NEJMra1402513 Moore, L. D., Le, T., & Fan, G. (2013). DNA methylation and its basic function. *Neuropsychopharmacology*, 38(1), 23–38. https://doi.org/10.1038/npp.2012.112 Osborne, A. J., Pearson, J. F., Noble, A. J., Gemmell, N. J., & Horwood, L. J. (2020). Cannabis use and epigenetic aging: Evidence from the Christchurch Health and Development Study. *Drug and Alcohol Dependence*, 216, 108228. https://doi.org/10.1016/j.drugalcdep.2020.108228 Pertwee, R. G. (2008). The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin. *British Journal of Pharmacology*, 153(2), 199–215. https://doi.org/10.1038/sj.bjp.0707442 Prini, P., Rusconi, F., Zamberletti, E., Gabaglio, M., Penna, F., Fasano, M., ... & Rubino, T. (2018). Adolescent THC exposure causes enduring prefrontal cortical disruption of GABAergic inhibition and dysregulation of sub-cortical dopamine function. *Scientific Reports*, 8(1), 1–13. https://doi.org/10.1038/s41598-018-34329-4 Schrott, R., Acharya, K., Iturra-Mena, A. M., Diwadkar, A., Hurd, Y. L., & Murphy, S. K. (2021). Cannabis use is associated with differential methylation in human sperm. *Epigenetics*, 16(7), 757–767. https://doi.org/10.1080/15592294.2020.1827722

Cannabis Use Is Linked to Epigenetic Changes, Scientists Discover

Heavy Cannabis Use and Colon Cancer: A Sobering New Study

Heavy Cannabis Use and Colon Cancer: A Sobering New Study

Recent research has sparked a heated debate about the risks of marijuana use, particularly for those battling serious illnesses like colon cancer. A study published on April 28, 2025, by researchers at the University of California San Diego School of Medicine found a striking correlation: colon cancer patients with a history of high cannabis use were more than 20 times more likely to die within five years of diagnosis compared to those without such a history. This finding, while alarming, raises important questions about cannabis’s impact on cancer outcomes and underscores the need for more research. Let’s dive into the details of the study, explore its implications, and consider the broader context of cannabis and cancer.

The Study: What the Researchers Found

The UC San Diego team analyzed electronic health records from over 1,000 colon cancer patients treated across the University of California Health system between 2012 and 2024. They focused on patients’ documented cannabis use prior to their cancer diagnosis, specifically those with a history of cannabis use disorder (CUD)—a clinical diagnosis indicating problematic, heavy use. After controlling for factors like age, sex, tumor staging, and cancer biomarkers, the results were stark: patients with CUD had a 56% chance of dying within five years, compared to just 5% for those without CUD. This translates to a 24-fold increased risk of mortality for heavy cannabis users.

Lead author Raphael Cuomo, an associate professor at UC San Diego’s Department of Anesthesiology, pointed out that heavy cannabis use may affect the immune system, mental health, and treatment behaviors—all of which could influence cancer outcomes. For instance, high cannabis use is often linked to depression and anxiety, which might hinder a patient’s ability to fully engage with their cancer treatment. The study suggests that these factors, rather than a direct biological effect of cannabis on cancer cells, may be driving the increased mortality risk.

The Context: Cannabis and Cancer Research

This study adds a new layer to the complex relationship between cannabis and cancer. On one hand, some research has suggested potential benefits. A 2019 study from Penn State College of Medicine found that certain synthetic cannabinoid compounds inhibited the growth of colon cancer cells in lab tests. Another 2020 study in mice showed that tetrahydrocannabinol (THC), the psychoactive compound in cannabis, could reduce inflammation and prevent colon cancer linked to ulcerative colitis by binding to cannabinoid receptor type 2 (CB2). These findings have fueled hope that cannabis might one day play a role in cancer treatment or prevention.

However, the UC San Diego study highlights a different side of the story. While lab studies show promise, real-world use of cannabis is far more complicated. The researchers noted that the high concentrations of DMS and DMDS detected on K2-18b, mentioned in a previous post, are thousands of times higher than on Earth, where they are produced by marine life. This comparison, while unrelated to cannabis, illustrates how context matters when interpreting chemical or biological effects. Similarly, the effects of cannabis on colon cancer patients may depend on usage patterns, individual health factors, and the presence of other conditions like mental health challenges.

A Critical Look: What’s Missing?

While the UC San Diego study is compelling, it’s not without limitations. First, it relies on retrospective data, meaning it can’t prove that cannabis use directly caused the higher mortality rates—it only shows an association. Patients with CUD might have other risk factors, like poor overall health or socioeconomic barriers, that weren’t fully accounted for. Second, the study doesn’t explore the mechanisms behind the increased mortality. Does cannabis weaken the immune system’s ability to fight cancer? Does it interfere with chemotherapy? Or is the issue more behavioral, with heavy users less likely to adhere to treatment plans? These questions remain unanswered.

Moreover, the study’s focus on heavy cannabis use—specifically CUD—means its findings may not apply to moderate or occasional users. A 2019 systematic review found no clear association between marijuana use and the development of colorectal cancer, though it noted increased risks for other cancers like testicular cancer among heavy users. This suggests that the risks may be dose-dependent, a nuance the UC San Diego study doesn’t fully address.

It’s also worth questioning the narrative around cannabis. The study has been widely shared on platforms like X, with posts framing it as a warning against marijuana use. Yet, this risks oversimplifying the issue. Cannabis isn’t a monolith—its effects vary depending on the strain, method of use, and individual factors. Vilifying cannabis outright, as some reactions suggest, ignores its potential benefits for symptom management, as noted by colorectal cancer survivors in a 2021 Fred Hutchinson Cancer Center study. Up to 40% of cancer patients report using cannabis to relieve symptoms like nausea and pain, often with positive outcomes.

Implications and the Path Forward

The UC San Diego study doesn’t claim cannabis causes colon cancer or directly worsens it. Instead, it highlights a concerning correlation that demands further investigation. With cannabis use on the rise—4.5 million young adults in the U.S. reported daily or near-daily use in 2023, according to the National Survey on Drug Use and Health—the stakes are high. This is especially true for medically vulnerable populations like cancer patients, who may turn to cannabis for relief but could inadvertently face risks if their use becomes heavy.

For patients, this study underscores the importance of open conversations with healthcare providers. If you’re a colon cancer patient considering cannabis, discuss your usage patterns with your oncology team. For researchers, the study is a call to action. We need prospective studies to track cannabis use before and after a cancer diagnosis, as well as research into the biological pathways—like immune system effects—that might explain these outcomes.

Conclusion: A Balanced Perspective

The UC San Diego study is a sobering reminder that cannabis, despite its growing acceptance, isn’t risk-free—especially for those with serious illnesses like colon cancer. Heavy use may be linked to worse outcomes, but the why and how remain unclear. At the same time, dismissing cannabis entirely ignores its potential benefits for symptom relief and even cancer prevention, as other studies suggest. The truth likely lies in the middle: cannabis can be both a help and a hindrance, depending on how it’s used and by whom. As we await more research, the best approach is caution, curiosity, and honest dialogue—both in the doctor’s office and in the public square.

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Sources

• University of California San Diego School of Medicine, April 28, 2025, published in Annals of Epidemiology.
• Penn State College of Medicine, 2019, published in Cannabis and Cannabinoid Research.
• Medical News Today, October 3, 2020, study on THC and colon cancer in mice.
• National Survey on Drug Use and Health, 2023 data on cannabis use among young adults.
• Fred Hutchinson Cancer Center, 2021, study on cannabis use among colorectal cancer survivors, published in Cancer Causes & Control.
• Systematic review on marijuana use and cancer risk, 2019, published in Cancer Epidemiology, Biomarkers & Prevention.

New York: You Can Grow Marijuana at Home

New York's Green Thumb: The State's Progressive Step Towards Homegrown Marijuana

In a landmark move, New York State has legalized the home cultivation of marijuana for adults aged 21 and over, marking a significant shift in the state's approach to cannabis regulation. This progressive step not only reflects the changing attitudes toward marijuana use but also empowers individuals with the freedom to grow their own plants for personal use.

Under the new guidelines, residents can cultivate up to three mature and three immature plants individually, with a maximum of six mature and six immature plants per household, regardless of the number of adults residing there. This initiative aims to provide a safe and regulated framework for home cultivation, ensuring that individuals can enjoy the benefits of marijuana without the risks associated with unregulated use.

The state has put forth clear regulations to ensure the safety and security of home cultivation. For instance, the use of flammable materials for at-home cannabis-based product extraction is prohibited due to safety concerns. Instead, residents are encouraged to explore alternative methods such as heat, water, or fermentation. Additionally, measures must be taken to prevent cannabis odor from becoming a nuisance to neighbors and to secure plants from unauthorized access or theft.

The legalization also comes with an educational push, providing resources for residents to learn about safe cultivation practices. The Office of Cannabis Management has made information readily available on its website and through a dedicated hotline, guiding individuals on everything from purchasing seeds to controlling indoor air quality to reduce the risk of mold and fungus.

This move by New York is not just about allowing the growth of marijuana plants; it's about fostering a responsible culture around cannabis use. It's about recognizing the therapeutic and recreational benefits of marijuana while also acknowledging the importance of regulation and education in preventing potential misuse.

As New Yorkers begin to exercise their newfound rights, it's essential to remain informed and compliant with the state's regulations. By doing so, residents can ensure that they are contributing to a safe and sustainable cannabis culture in New York State.

This news will not be well accepted by people who value quality of life.  New York is clearly lost. Whether or not this state will return to reason is left to be seen. However, we can assume that it is on a downward spiral and will bring about election changes when crime gets worse and quality of life disappears.  Marijuana use as recreation is not safe, see:Sacerdotus: Dangers of Marijuana Use.  Studies are already coming out showing that the legalization of it has made things worse in states that have legalized it.  

For more detailed information on the rules and regulations of homegrown marijuana in New York, interested individuals can visit the official state cannabis website or consult the comprehensive guide provided by local news outlets.

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References:

https://pix11.com/news/local-news/marijuana-in-ny-nj/growing-weed-allowed-in-new-york-homes/

: New York State's official guidelines on home cultivation of cannabis.

: Local news outlet's detailed breakdown of the rules for legally growing marijuana at home in NY.

Dangers of Marijuana Use

Today is April 20 or 420 which is the street code for marijuana or weed. Like with other evils that have been legalized in the United States such as abortion, so-called same-sex marriage, euthanasia, and so on, Marijuana has joined the ranks of now socially accepted behavior. I remember when I was a kid. Cops used to visit our classroom. One brought a red suitcase display with various drugs. He explained to us about each drug and the dangers surrounding their use. 

Shortly afterward, I remember the cartoon program that aired on all networks containing the popular characters at the time. This cartoon was geared towards teaching kids about drugs and why they are not good.  How times have changed! Now it is celebrated!  Drug use is now a thing that even our own government promotes. You will even find people who will defend the use of Marijuana justifying it by claiming it is legalized, therefore it is good. This is not how ethics or morality works or even healthcare. The majority does not decide what is right or wrong. Things are intrinsically good or evil or can be abused. Marijuana is one such thing. While it is natural, it is a plant, and it can be abused. 

Medicinal Marijuana does have its benefits, but this form is controlled. Only the beneficial parts remain. Recreational marijuana is a different story. It is harmful to the smoker's health and those around the smoker. States that have legalized its use have seen a rise in crime. In New York, California, and Massachusetts, we see a huge rise in crime. People are being pushed into trains, into traffic, punched, slapped, and stabbed. Most of the attackers are labeled as "mentally ill" but upon closer inspection, they are high on drugs, namely, Marijuana and Synthetic marijuana or "K2."  

These cities and Democratic-run states even encourage drug use. Instead of helping drug addicts, they give them syringes and even have places in parks or on the street where they can shoot up their drugs. The syringes are then discarded on the street, park grounds, alleys, and sidewalks where innocent people or pets can jab themselves with them by accident. Despite being against state and federal law (Federal prosecutor threatens to shut down NYC overdose prevention centers - CBS New York (cbsnews.com)), these injection safe spaces were created and are active.

Now the idea for this handing out of syringes and creating "safe injecting sites" was to limit the spread of HIV, Hepatitis, and other intravenous pathogens or viruses and to prevent addicts from dangerous withdrawal symptoms. Naloxone or Narcan are provided with syringes. This is a drug administered via a nasal spray that can potentially save the life of someone who has overdosed by reversing the effects.  

However, things did not work out as planned.  As stated, used syringes are being disposed of improperly and after injection along with the Narcan (unused), addicts are seen in a zombie-like state, acting irrationally or feral, passed out, and in some cases, deceased from a heavy overdose. At St. Mary's Park in my hometown The Bronx in New York City, residents have been complaining about this for years. In a few months, over 6,000 used syringes were found on the grounds of the park. Last year alone, over 30,000 were found.  See:

Drug needles, syringes litter a Bronx park. This organization is taking action. - CBS New York (cbsnews.com)

Residents worry about an ongoing safety risk at St. Mary's Park: Discarded needles - Mott Haven Herald

Used needles, syringes litter one of the only parks in the South Bronx - CBS New York (cbsnews.com)

So while the intention was good-natured, it backfired. The government and health officially literally believed that addicts have the discipline and temperance to "shoot up" responsibly if that makes sense. Instead, overdosing and deaths due to them have increased in NYC, see:

(91) NYC drug overdose deaths skyrocketing, experts explain - YouTube

Report details "unprecedented" number of drug overdoses in NYC (youtube.com)

This is not the way to help drug addicts or even alcoholics. The same was done with Marijuana. The legalization of Marijuana as recreational was done in an attempt to raise money for the government. Instead of having drug dealers make millions, why not the state? The state became the drug dealer. They do not care about citizens or those with addiction. Many areas are now rethinking their laws that legalized Marijuana use. Thailand is one such nation doing this after there was a rise in crime and mental health problems.  

The Dangers of Smoking Marijuana: A Closer Look

Marijuana, often referred to as weed, pot, or cannabis, is a topic of significant debate and research due to its widespread use and the shifting legal landscape surrounding it. While some advocate for its benefits, particularly in medical contexts, it is crucial to acknowledge the potential risks associated with its use, especially when smoked. Here, we delve into the dangers of smoking marijuana, supported by references to recent studies and health resources.

Marijuana, while it may be something natural – a plant – it is still dangerous. It is the most used illicit drug in the United States and its effects come instantly once a person smokes it since the smoke enters the lungs and then the bloodstream via the alveoli immediately. These effects can last over three hours.

• Marijuana is a psychoactive drug which means that it alters the mind and how it perceives reality.
• It distorts what we hear, see, smell, taste, and touch. Our perception of time is disrupted. Marijuana also disrupts learning, and memory and takes away coordination.
• Users of the drug have trouble concentrating, and cannot problem-solve or think clearly. The heartbeat increases while blood pressure drops dramatically. So much for recreation/fun right?
• These symptoms are due to the tetrahydrocannabinol or THC chemical which affects the nerve cells in the brain by disrupting anandamides because both have nearly identical molecular structures. Anandamides ironically are natural marijuana-like chemicals that the brain produces. It helps with pain relief.
• Furthermore, the use of marijuana weakens the immune system due to the presence of THC. Smoking it also poses dangers to the lungs because it contains 50% more carcinogens than regular cigarettes. It will also bring about anxiety, panic attacks, depression, and paranoia.
• The verdict is that using marijuana for recreational reasons is not a good idea and is hardly recreational or fun.

Impact on Brain Health

Research indicates that marijuana can cause permanent IQ loss, particularly when use begins at a young age. This loss in cognitive function does not appear to be reversible, even after ceasing marijuana use.

Mental Health Concerns

There is a documented link between marijuana use and various mental health issues, including depression, anxiety, and psychotic episodes. While causation is not fully established, the correlation is a cause for concern, particularly among younger users who are at a higher risk of addiction.

Physical Health Risks

Smoking marijuana can lead to respiratory issues similar to those caused by smoking tobacco. This includes an increased risk of bronchitis, lung infections, and potential damage to lung tissue. Additionally, there are cardiovascular risks, with some studies suggesting a link between heavy marijuana use and an increased risk of heart failure and other vascular diseases.

Exploring the Complex Relationship Between Marijuana and Cancer

The intersection of marijuana use and cancer is a topic of growing interest and research, particularly as the legal landscape surrounding cannabis continues to evolve. The plant Cannabis sativa, commonly known as marijuana, has been utilized in herbal remedies for centuries, and modern science has begun to shed light on its potential therapeutic and adverse health effects.

Cannabinoids, the biologically active components of marijuana, have been identified and extensively studied, with delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) being the most well-known. These compounds have shown promise in managing symptoms related to cancer and its treatments, such as nausea, pain, and loss of appetite. For instance, pharmaceutical forms of THC and a synthetic cannabinoid called nabilone have received FDA approval for treating conditions like chemotherapy-induced nausea and vomiting.

However, the relationship between marijuana and cancer risk is complex and not fully understood. While some studies suggest a potential increased risk of certain cancers, such as lung, head, and neck cancers, associated with long-term cannabis smoking, the quality of this research is not as robust as the evidence linking tobacco use to cancer. Moreover, there is insufficient evidence to conclude that marijuana use is associated with a higher risk of other forms of cancer, including prostate, cervical, penile, and colorectal cancers.

The method of marijuana consumption also plays a significant role in its health effects. Inhaled marijuana, whether smoked or vaporized, introduces a range of chemicals into the body, some of which are known irritants and carcinogens found in tobacco smoke. This exposure can lead to lung irritation, acute bronchospasm, and an increased risk of chronic bronchitis and lung cancer. Conversely, edible forms of marijuana, which are absorbed through the gastrointestinal tract, produce different psychoactive effects and have a delayed onset of action.

It's important to note that the legalization of marijuana in various states has led to increased usage and a greater need for public education on its potential health impacts. The Centers for Disease Control and Prevention (CDC) and other health organizations continue to study marijuana's health effects, including its potential to manage the side effects of cancer therapies.

Ongoing research is essential to fully understand the implications of marijuana use on cancer risk and to guide patients and healthcare providers in making informed decisions about its therapeutic use. As with any substance, moderation and medical guidance are key to minimizing risks and maximizing potential benefits.

Effects on Athletic Performance

Timing, movement, and coordination are essential for athletic performance, and these can be adversely affected by marijuana use. The impairment of these physical capabilities can have a significant negative impact on athletes' performance levels.

Risks During Pregnancy and Breastfeeding

Pregnant women and nursing mothers should be particularly cautious, as marijuana use can affect fetal growth, potentially leading to premature birth or stillbirth. Furthermore, THC and other chemicals can be transferred to the child through breast milk, impacting the child's development.

Influence on Daily Life

The use of marijuana is not without consequences in one's daily life. Studies have shown that regular users may experience relationship problems, educational setbacks, lower career achievement, and overall reduced life satisfaction.

Addiction and Dependency

Contrary to some beliefs, marijuana can be addictive. The risk of addiction is higher for those who begin using at a younger age, with approximately 1 in 6 becoming addicted if they start before age 18. For adults, the addiction rate is around 1 in 10.

Conclusion

While the conversation around marijuana is complex and multifaceted, it is essential to consider the potential dangers of its use. Smoking marijuana, in particular, carries risks that can affect an individual's mental and physical health, as well as their overall quality of life. As research continues to evolve, it is important for individuals to stay informed and weigh the risks when making decisions about marijuana use.

If you are smart and care about your life and others, do not use it! It will just remove days from your life and the lives of others. It is just not worth it.  Why would you want to be high? Why do you want to "escape from the world" by being "out of your mind?" Why become a zombie?  People who just marijuana and promote it seem to be afraid of life and reality. They think this plant will make things disappear via delusions and psychedelic experiences. News flash, life, and reality remain the same even after the high.  

For more detailed information and further reading on the subject, the following resources provide valuable insights: SAMHSA, WebMD, Cleveland Clinic, Scientific American, and Healthline. It is always recommended to consult with healthcare professionals when seeking advice on substance use and its effects.

Other sources:

Is marijuana legalization driving increases in violent crime? | The Hill

Luke Niforatos: Bad things happen when states legalize weed | Pittsburgh Post-Gazette

New study reveals increase in marijuana-related incidents since legalization in Illinois (fox32chicago.com)

America, take note: Thailand is set to REVERSE weed legalization after spike in cannabis-related mental health issues and crime - with government calling pot 'a big problem' | Daily Mail Online

Marijuana use during pregnancy linked to increase in childhood cancers, Duke study finds - ABC11 Raleigh-Durham

Genomic study links cannabis abuse to multiple health problems | YaleNews

Many Americans wrongly believe exposure to marijuana smoke is safer than tobacco, study finds | CNN

Genome study unveils genetic ties between cannabis use disorder and lung cancer risk (news-medical.net)

Marijuana & Lung Cancer Risk - Mayo Clinic Health System

MTV's VMAs - Praising Drug Use, LGBT Immorality & Trashiness

MTV had its annual Video Music Awards yesterday and once again it has shown itself as a cesspool of immorality, raunchiness, stupidity and lack of talent.  The show was hosted by Miley Cyrus who turned the even into a psychedelic display of LGBT brainwashing mixed with sexual tones and trashy displays.  She even promoted marijuana use.

During the show, when Nicki Minaj went to accept her award, she called out Miley for comments made during an interview. The drama on stage seemed staged though. However, what apparently took the attention was when Kanye West accepted an award from Tylor Swift who he disrespected in a  previous award show by storming the stage and telling her that Beyonce deserved to win.

West spoke for what it seemed like 20 minutes. His speech was irrational.  He even pointed that he "smoked something" before the awards.  At the end of the speech he stated that he will run for president in 2020.  No one is sure if he was serious of if that was just the affect of the drugs he was on.

This show has gone downhill from what I remember. It is overly trashy, hippish, immoral and clearly geared towards the LGBT agenda.  The youth are inundated with the promotion of drug use, trashy behavior, sexual tones and homosexuality.  Then we wonder why our youth is lost in drugs, promiscuity and gender confusion.

Parents need to take back their kids or watch them rot in the cesspool of the "music" industry if I can call it that.  Most of the "music" today is computer generated. The art of music has been lost it seems.  







Source:

http://www.cnn.com/2015/08/31/entertainment/vmas-2015-kanye-miley-feat/

http://www.theverge.com/2015/8/30/9229745/mtv-vma-awards-2015-miley-cyrus-host

http://www.nytimes.com/2015/09/01/arts/music/kanye-west-president-2015-vma-speech.html?_r=0